Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9459074 | 0.83 | ALDH1A1 (0.55) | TSHRALDH1A1POLBCYP2C19MEN1 | |
| SCHEMBL6359410 | 0.83 | ALDH1A1 (0.55) | TSHRALDH1A1POLBCYP2C19MEN1 | |
| SCHEMBL9459079 | 0.83 | ALDH1A1 (0.55) | TSHRALDH1A1POLBCYP2C19MEN1 | |
| SCHEMBL2416170 | 0.80 | TDP1 (0.50) | TDP1GPR35MAPTTSHRALDH1A1 | |
| SCHEMBL1645029 | 0.78 | ALDH1A1 (0.52) | TDP1GPR35MAPTTSHRALDH1A1 | |
| SCHEMBL9113733 | 0.78 | MAPT (0.44) | TDP1MAPTTSHRALDH1A1POLB | |
| SCHEMBL21685749 | 0.78 | ALDH1A1 (0.41) | TDP1GPR35MAPTTSHRALDH1A1 | |
| SCHEMBL6278459 | 0.78 | ALDH1A1 (0.50) | TDP1GPR35MAPTTSHRALDH1A1 | |
| SCHEMBL10581369 | 0.77 | HTT (0.51) | TDP1GPR35MAPTALDH1A1POLB | |
| SCHEMBL4373852 | 0.76 | TDP1 (0.46) | TDP1GPR35MAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303826-B1 | SUBSTITUTED 2-NITRO METAPHENYLENE DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING KERATINOUS FIBRES AND ESPECIALLY HUMAN HAIR | L'OREAL (FR) | 1991-02-27 | — | — | EP | claimed |