Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359410 | 1.00 | ALDH1A1 (0.55) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL9459074 | 1.00 | ALDH1A1 (0.55) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL3932099 | 0.88 | ALDH1A1 (0.53) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL3137939 | 0.86 | ALDH1A1 (0.51) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL2064880 | 0.85 | ALDH1A1 (0.58) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL28123482 | 0.84 | POLB (0.54) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL9820264 | 0.83 | TDP1 (0.42) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL1665641 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL1666014 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL11295444 | 0.82 | POLB (0.35) | ALDH1A1TSHRPOLBCYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262333-A | Fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1993-11-16 | — | — | US | disclosed |
| EP-0371253-A2 | Method and reagents for detecting amphetamine and/or d-methamphetamine in biological samples | ABBOTT LABORATORIES (US) | 1990-06-06 | — | — | EP | disclosed |