SCHEMBL9820439

SCHEMBL9820439

C=CC(=O)OC(COc1ccccc1)(OCC)OCC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.49
TEAD1 P28347 1/20 0.37
TEAD3 Q99594 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALOX15 P16050 1/20 0.37
SMN1; SMN2 Q16637 4/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
RAB9A P51151 4/20 0.36
NPC1 O15118 3/20 0.36
PKM P14618 1/20 0.36
LTA4H P09960 1/20 0.36
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
MAPT P10636 1/20 0.35
ALPL P05186 1/20 0.35
ALPI P09923 1/20 0.35
ALPG P10696 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7631124 0.85 KDM4E (0.40) THRBTDP1SMN1; SMN2KMT2AKDM4E
SCHEMBL9820438 0.83 THRB (0.40) THRBTEAD1TEAD3SMN1; SMN2KMT2A
SCHEMBL8982100 0.80 THRB (0.51) THRBTEAD1TEAD3TDP1ALOX15
SCHEMBL10794140 0.78 THRB (0.55) THRBTEAD1TEAD3ALOX15SMN1; SMN2
SCHEMBL691151 0.78 THRB (0.49) THRBTDP1SMN1; SMN2KMT2AMEN1
SCHEMBL10790276 0.77 THRB (0.54) THRBTEAD1TEAD3ALOX15SMN1; SMN2
SCHEMBL2768277 0.76 THRB (0.43) THRBSMN1; SMN2KMT2AKDM4ERAB9A
SCHEMBL8731568 0.76 THRB (0.40) THRBSMN1; SMN2TSHRALDH1A1CYP3A4
SCHEMBL9042375 0.74 THRB (0.59) THRBTEAD1TEAD3ALOX15SMN1; SMN2
SCHEMBL4904711 0.73 THRB (0.40) THRBSMN1; SMN2TSHRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0128014-B2 PHOTOPOLYMERIZABLE COMPOSITION, PRODUCTS MADE THEREFROM AND PROCESSES FOR PREPARING SUCH PRODUCTS MORTON THIOKOL, INC. (US) 1991-08-21 EP disclosed
EP-0128014-B1 PHOTOPOLYMERIZABLE COMPOSITION, PRODUCTS MADE THEREFROM AND PROCESSES FOR PREPARING SUCH PRODUCTS MORTON THIOKOL, INC. (US) 1988-03-09 EP disclosed
US-4610951-A Process of using a flexible, fast processing photopolymerizable composition DYNACHEM CORPORATION (US) 1986-09-09 US disclosed
US-4539286-A PRINTED CIRCUITS DYNACHEM CORPORATION (US) 1985-09-03 US disclosed
EP-0128014-A2 Photopolymerizable composition, products made therefrom and processes for preparing such products MORTON THIOKOL, INC. (US) 1984-12-12 EP disclosed