Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820439 | 0.85 | THRB (0.49) | KDM4EALDH1A1SMN1; SMN2GAATHRB | |
| SCHEMBL7622862 | 0.82 | KDM4E (0.37) | KDM4EALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL7625531 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL19255443 | 0.75 | THRB (0.32) | KDM4EALDH1A1SMN1; SMN2GAATHRB | |
| SCHEMBL8557158 | 0.75 | PLK1 (0.44) | SMN1; SMN2POLBTHRBMEN1KMT2A | |
| SCHEMBL26048815 | 0.75 | THRB (0.53) | KDM4EALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL31451650 | 0.75 | ALDH1A1 (0.43) | KDM4EALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL21779001 | 0.74 | THRB (0.58) | KDM4EALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL93929 | 0.74 | THRB (0.46) | KDM4EALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL8731568 | 0.73 | THRB (0.40) | ALDH1A1SMN1; SMN2THRBTP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942303-A | CURABLE ADDITION TERPOLYMER BASED ON 2,2-BIS(P-(METH)ACRYLOYL -(P-(METH)ACRYLOYLOXY(ALKYLOXY)N-PHENYL)PROPANES, WHERE N IS 2-5, AND UNSATURATED COMPOUND; IMPACT STRENGTH; LOW SPECIFIC GRAVITY; LIGHTWEIGHT; EYEGLASSES; CONTACT LENSES; LENSES | NOF CORPORATION (JP) | 1999-08-24 | — | — | US | claimed |
| EP-0828167-B1 | Resin composition for polymerization casting and optical material | NOF CORP (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5942303-A | CURABLE ADDITION TERPOLYMER BASED ON 2,2-BIS(P-(METH)ACRYLOYL -(P-(METH)ACRYLOYLOXY(ALKYLOXY)N-PHENYL)PROPANES, WHERE N IS 2-5, AND UNSATURATED COMPOUND; IMPACT STRENGTH; LOW SPECIFIC GRAVITY; LIGHTWEIGHT; EYEGLASSES; CONTACT LENSES; LENSES | NOF CORPORATION (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0828167-A2 | Resin composition for polymerization casting and optical material | NOF CORPORATION (JP) | 1998-03-11 | — | — | EP | disclosed |