Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18532479 | 0.81 | ALDH1A1 (0.44) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL19992867 | 0.79 | TDP1 (0.54) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL18416407 | 0.79 | TDP1 (0.54) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL18421307 | 0.76 | TDP1 (0.50) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL18416410 | 0.76 | TDP1 (0.50) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL23057902 | 0.74 | TDP1 (0.48) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL13966434 | 0.74 | TDP1 (0.48) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL1455133 | 0.74 | TDP1 (0.58) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL20213681 | 0.73 | ALDH1A1 (0.60) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL20213682 | 0.73 | ALDH1A1 (0.60) | TDP1ALDH1A1TSHRCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187501-B1 | PROCESS FOR PREPARING INDOLE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-11-13 | — | — | EP | disclosed |
| US-4732654-A | CONDENSATION OF ANILINE WITH ETHYLENE GLYCOL; CATALYST | MITSUI TOATSU CHEMICALS, INC. (JP) | 1988-03-22 | — | — | US | disclosed |