Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 4/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607649 | 0.95 | ESR1 (0.54) | TSHRMAPK1LMNAESR1CYP1A2 | |
| SCHEMBL5606791 | 0.89 | ESR1 (0.51) | TSHRMAPK1LMNAESR1CYP1A2 | |
| SCHEMBL27345528 | 0.85 | TSHR (0.53) | TSHRMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL27956127 | 0.85 | TSHR (0.53) | TSHRMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11800607 | 0.85 | LMNA (0.50) | TSHRMAPK1LMNAESR1CYP1A2 | |
| SCHEMBL868458 | 0.85 | TSHR (0.53) | TSHRMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL5174859 | 0.85 | TSHR (0.53) | TSHRMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL27769186 | 0.85 | TSHR (0.53) | TSHRMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL12035802 | 0.83 | KMT2A (0.57) | MAPK1LMNAESR1CYP1A2CYP2C19 | |
| SCHEMBL5617201 | 0.83 | KMT2A (0.57) | MAPK1LMNAESR1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240184-B1 | ALPHA-METHYLCINNAMIC ACID ESTER DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | MITSUBISHI RAYON CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4751018-A | DISCOLORATION INHIBITION | MITSUBISHI RAYON COMPANY LTD. (JP) | 1988-06-14 | — | — | US | disclosed |
| EP-0240184-A2 | Alpha-Methylcinnamic acid ester derivative and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |