Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820493 | 0.84 | KDM4E (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL11783664 | 0.76 | ALDH1A1 (0.43) | ALDH1A1RAB9ALMNANPC1SMN1; SMN2 | |
| SCHEMBL10495113 | 0.76 | BCHE (0.35) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL10495117 | 0.74 | NPC1 (0.35) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL21091032 | 0.72 | ALDH1A1 (0.51) | ALDH1A1RAB9ALMNANPC1SMN1; SMN2 | |
| SCHEMBL9533340 | 0.72 | KDM4E (0.61) | ALDH1A1RAB9ALMNANPC1SMN1; SMN2 | |
| SCHEMBL10495079 | 0.70 | KDM4E (0.51) | ALDH1A1RAB9ALMNANPC1SMN1; SMN2 | |
| SCHEMBL11565050 | 0.69 | ALDH1A1 (0.49) | ALDH1A1RAB9ALMNANPC1SMN1; SMN2 | |
| SCHEMBL31536902 | 0.69 | ALDH1A1 (0.65) | ALDH1A1RAB9ALMNANPC1SMN1; SMN2 | |
| SCHEMBL11609747 | 0.69 | ALDH1A1 (0.54) | ALDH1A1RAB9ALMNANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217747-B1 | NEMATOCIDAL AGENTS | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | claimed |
| US-4694014-A | 1,3,4-THIADIAZOLES | CIBA-GEIGY CORPORATION (US) | 1987-09-15 | — | — | US | claimed |
| EP-0217747-A2 | Nematocidal agents | CIBA-GEIGY AG (CH) | 1987-04-08 | — | — | EP | claimed |
| EP-0217747-B1 | NEMATOCIDAL AGENTS | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | disclosed |
| US-4694014-A | 1,3,4-THIADIAZOLES | CIBA-GEIGY CORPORATION (US) | 1987-09-15 | — | — | US | disclosed |
| EP-0217747-A2 | Nematocidal agents | CIBA-GEIGY AG (CH) | 1987-04-08 | — | — | EP | disclosed |