Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.61 |
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565441 | 0.78 | TERT (0.54) | KDM4ERAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL1424929 | 0.77 | KDM4E (1.00) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL9820493 | 0.74 | KDM4E (0.53) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL9532116 | 0.72 | KMT2A (0.50) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL29870798 | 0.71 | KDM4E (0.77) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL15671504 | 0.71 | KDM4E (0.77) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL17135790 | 0.69 | KDM4E (0.74) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL11982530 | 0.69 | KDM4E (0.74) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL971007 | 0.69 | KDM4E (0.74) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL8143194 | 0.69 | KDM4E (0.74) | KDM4ERAB9ANPC1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285565-B1 | 2-MERCAPTO-5-PYRIDYL-1,3,4-OXADIAZOLES AND 1,3,4-THIADIAZOLES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS NEMATICIDAL AGENTS | CIBA-GEIGY AG (CH) | 1993-09-15 | — | — | EP | claimed |
| US-4894380-A | NEMATOCIDES | CIBA-GEIGY CORPORATION (US) | 1990-01-16 | — | — | US | claimed |
| EP-0285565-A2 | 2-Mercapto-5-pyridyl-1,3,4-oxadiazoles and 1,3,4-thiadiazoles, process for their preparation and their use as nematicidal agents | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | claimed |
| EP-0285565-B1 | 2-MERCAPTO-5-PYRIDYL-1,3,4-OXADIAZOLES AND 1,3,4-THIADIAZOLES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS NEMATICIDAL AGENTS | CIBA-GEIGY AG (CH) | 1993-09-15 | — | — | EP | disclosed |
| US-4894380-A | NEMATOCIDES | CIBA-GEIGY CORPORATION (US) | 1990-01-16 | — | — | US | disclosed |
| EP-0285565-A2 | 2-Mercapto-5-pyridyl-1,3,4-oxadiazoles and 1,3,4-thiadiazoles, process for their preparation and their use as nematicidal agents | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | disclosed |