Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820690 | 1.00 | MAOA (0.31) | MAOAMAOBKMT2A | |
| SCHEMBL9820652 | 0.78 | MAOA (0.39) | MAOAMAOBKMT2A | |
| SCHEMBL9869957 | 0.76 | CYP1A2 (0.35) | KMT2A | |
| SCHEMBL9869965 | 0.76 | CYP1A2 (0.35) | KMT2A | |
| SCHEMBL9820813 | 0.73 | MAOA (0.42) | MAOAKMT2A | |
| SCHEMBL9820650 | 0.69 | MAOA (0.31) | MAOA | |
| SCHEMBL9820645 | 0.69 | MAOA (0.31) | MAOA | |
| SCHEMBL15773671 | 0.66 | NPC1 (0.35) | KMT2A | |
| SCHEMBL5615886 | 0.65 | ACMSD (0.37) | — | |
| SCHEMBL8494999 | 0.64 | ACMSD (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |