Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1438726 | 0.80 | DRD2 (0.46) | DRD2DRD3 | |
| SCHEMBL28288794 | 0.79 | DRD2 (0.42) | DRD2DRD3HTR2C | |
| SCHEMBL1437913 | 0.79 | NPC1 (0.43) | DRD2DRD3 | |
| SCHEMBL18434126 | 0.78 | DRD2 (0.46) | DRD2DRD3 | |
| SCHEMBL15159990 | 0.78 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3DRD2DRD3 | |
| SCHEMBL28401510 | 0.77 | ALDH1A1 (0.43) | SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL11170852 | 0.77 | DRD2 (0.62) | DRD2DRD3HTR2C | |
| SCHEMBL7913038 | 0.76 | — | — | |
| SCHEMBL7907786 | 0.76 | — | — | |
| SCHEMBL656231 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |