Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | EP300 | Q09472 | 9/20 | 0.41 |
| ▸ | KDM1A | O60341 | 5/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801186 | 0.76 | HTR2C (0.49) | HTR2CKDM1AMAOBHTR2AHTR2B | |
| SCHEMBL9820788 | 0.73 | HTR2C (0.49) | HTR2CKDM1AMAOBHTR2AHTR2B | |
| SCHEMBL300623 | 0.72 | HTR2C (0.67) | HTR2C | |
| SCHEMBL4247865 | 0.71 | GBA1 (0.59) | EP300CREBBP | |
| Hydrochloric Acid SCHEMBL23858205 | 0.71 | HTR2C (0.68) | HTR2C | |
| SCHEMBL18892649 | 0.70 | EP300 (0.45) | EP300CREBBP | |
| Hydrochloric Acid SCHEMBL7400329 | 0.70 | GBA1 (0.58) | EP300CREBBP | |
| SCHEMBL9597729 | 0.69 | P2RY14 (0.44) | HTR2CEP300 | |
| SCHEMBL30075690 | 0.69 | P2RY14 (0.44) | HTR2CEP300 | |
| SCHEMBL23873276 | 0.69 | P2RY14 (0.44) | HTR2CEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188887-B1 | TERTIARY AMINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-02 | — | — | EP | disclosed |
| EP-0188887-A1 | Tertiary amine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-07-30 | — | — | EP | disclosed |