Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 16/20 | 0.49 |
| ▸ | HTR2B | P41595 | 13/20 | 0.44 |
| ▸ | HTR2A | P28223 | 9/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801186 | 0.81 | HTR2C (0.49) | HTR2CHTR2BHTR2AKDM1ASLC6A2 | |
| SCHEMBL20080189 | 0.76 | HTR2C (0.66) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL15415942 | 0.74 | HTR2C (0.63) | HTR2CHTR2BHTR2AKDM1ASLC6A2 | |
| SCHEMBL28950360 | 0.73 | SLC6A2 (0.50) | HTR2CHTR2BHTR2AKDM1ASLC6A2 | |
| SCHEMBL9820835 | 0.73 | HTR2C (0.41) | HTR2CHTR2BHTR2AKDM1AMAOB | |
| SCHEMBL25069257 | 0.72 | KDM1A (0.54) | HTR2CKDM1ASLC6A2SLC6A3MAOB | |
| SCHEMBL15213072 | 0.72 | KDM1A (0.42) | HTR2CHTR2BKDM1ASLC6A2SLC6A4 | |
| SCHEMBL22436649 | 0.72 | SLC6A2 (0.45) | HTR2CKDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15201821 | 0.72 | KDM1A (0.42) | HTR2CHTR2BKDM1ASLC6A2SLC6A4 | |
| SCHEMBL15201822 | 0.72 | KDM1A (0.42) | HTR2CHTR2BKDM1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188887-B1 | TERTIARY AMINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-02 | — | — | EP | disclosed |
| EP-0188887-A1 | Tertiary amine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-07-30 | — | — | EP | disclosed |