Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.49 |
| ▸ | HTR2B | P41595 | 11/20 | 0.44 |
| ▸ | HTR2A | P28223 | 7/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820788 | 0.81 | HTR2C (0.49) | HTR2CHTR2BHTR2AKDM1ASLC6A2 | |
| SCHEMBL11965119 | 0.79 | HTR2C (0.63) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL11902887 | 0.79 | HTR2C (0.63) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL22436649 | 0.76 | SLC6A2 (0.45) | HTR2CCNR2KDM1ASLC6A2SLC6A4 | |
| SCHEMBL9820835 | 0.76 | HTR2C (0.41) | HTR2CHTR2BHTR2AKDM1AMAOB | |
| SCHEMBL16585035 | 0.75 | HTR2C (0.66) | HTR2CHTR2BHTR2AKDM1ASLC6A2 | |
| SCHEMBL17080568 | 0.75 | HTR2C (0.41) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL4893904 | 0.75 | HTR2C (0.66) | HTR2CHTR2BHTR2AKDM1ASLC6A2 | |
| SCHEMBL16569276 | 0.75 | HTR2C (0.41) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL13591154 | 0.75 | HTR2C (0.63) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006098554-A1 | NOVEL COMPOUNDS, ISOMER THEREOF OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2006-09-21 | — | — | WO | disclosed |
| EP-0188887-B1 | TERTIARY AMINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-02 | — | — | EP | disclosed |
| EP-0188887-A1 | Tertiary amine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-07-30 | — | — | EP | disclosed |