Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 6/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8110870 | 0.95 | GNAI3 (0.43) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL9820795 | 0.93 | GNAI3 (0.41) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL4723807 | 0.93 | MEN1 (0.36) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL4721777 | 0.87 | GNAI3 (0.34) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL4723752 | 0.85 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL946195 | 0.80 | SIGMAR1 (0.34) | GBA1 | |
| SCHEMBL4724871 | 0.79 | — | — | |
| SCHEMBL947066 | 0.78 | SIGMAR1 (0.31) | — | |
| SCHEMBL4723708 | 0.77 | — | — | |
| SCHEMBL948057 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |