Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820655 | 0.84 | BCL2L1 (0.44) | CNR1CNR2BCL2L1MEN1KMT2A | |
| SCHEMBL10469228 | 0.81 | KMT2A (0.39) | CNR1CNR2BCL2L1ALDH1A1MEN1 | |
| SCHEMBL9820695 | 0.81 | CNR1 (0.43) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL13696934 | 0.78 | NPC1 (0.43) | CNR1CNR2BCL2L1KMT2ALMNA | |
| SCHEMBL424526 | 0.75 | AKR1C4 (0.58) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL9823872 | 0.74 | ALDH1A1 (0.53) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL4122359 | 0.74 | CNR2 (0.44) | CNR1CNR2BCL2L1ALDH1A1MEN1 | |
| SCHEMBL14141253 | 0.72 | ALDH1A1 (0.52) | CNR1CNR2ALDH1A1LMNAKDM4E | |
| SCHEMBL10469179 | 0.72 | BCL2L1 (0.50) | BCL2L1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL123067 | 0.72 | AKR1C2 (0.64) | BCL2L1ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1022685-C | Hydrofluorene derivatives | OTSUKA PHARMA CO LTD (JP) | 1993-11-10 | — | — | CN | disclosed |
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |