Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9821006 | 0.99 | BLM (0.47) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| SCHEMBL9820972 | 0.86 | ADRB2 (0.48) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| SCHEMBL9821113 | 0.86 | ADRB2 (0.41) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| SCHEMBL9821038 | 0.78 | ADRB2 (0.51) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| SCHEMBL10535066 | 0.77 | ADRB2 (0.43) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| SCHEMBL9820974 | 0.73 | ADRB2 (0.58) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| SCHEMBL9820963 | 0.73 | LMNA (0.44) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| SCHEMBL10534049 | 0.72 | ADRB2 (0.43) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| SCHEMBL10717339 | 0.70 | NPSR1 (0.35) | — | |
| SCHEMBL9821154 | 0.69 | ADRB2 (0.43) | ADRB2HIF1AADRB1CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224001-B1 | ANTHRANILONITRILE DERIVATIVES AND RELATED COMPOUNDS AS USEFUL AGENTS FOR PROMOTING GROWTH, IMPROVING FEED EFFICIENCY, AND FOR INCREASING THE LEAN MEAT TO FAT RATIO OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1991-03-20 | — | — | EP | claimed |
| US-4863959-A | Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1989-09-05 | — | — | US | claimed |