Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821168 | 0.84 | MEN1 (0.52) | MAPTLMNAGAAAKR1C3AKR1C2 | |
| SCHEMBL9820960 | 0.84 | MEN1 (0.52) | MAPTLMNAGAAAKR1C3AKR1C2 | |
| SCHEMBL10629455 | 0.83 | HCAR3 (0.52) | MAPTLMNAGAAALDH3A1AKR1C3 | |
| SCHEMBL9821056 | 0.83 | MAPT (0.47) | MAPTLMNAGAAAKR1C3AKR1C2 | |
| SCHEMBL9820944 | 0.78 | MAPT (0.44) | MAPTLMNAGAAAKR1C3AKR1C2 | |
| SCHEMBL10631223 | 0.77 | ALDH3A1 (0.57) | MAPTLMNAGAAALDH3A1NPSR1 | |
| SCHEMBL15483224 | 0.73 | MAPT (0.49) | MAPTLMNAGAAALDH3A1KMT2A | |
| SCHEMBL10643719 | 0.72 | MAPT (0.45) | MAPTLMNAGAAALDH3A1NPSR1 | |
| SCHEMBL1663522 | 0.71 | MAPT (0.54) | MAPTLMNAGAAALDH3A1NPSR1 | |
| SCHEMBL31743760 | 0.71 | ALDH3A1 (0.47) | MAPTLMNAGAAALDH3A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220614-B1 | DIRECT HAIR DYEING COMPOSITION CONTAINING DERIVATIVES OF NITRODIPHENYL AMINE | Henkel Kommanditgesellschaft auf Aktien (DE) | 1991-01-23 | — | — | EP | disclosed |
| EP-0220614-A1 | Direct hair dyeing composition containing derivatives of nitrodiphenyl amine | Henkel Kommanditgesellschaft auf Aktien (DE) | 1987-05-06 | — | — | EP | disclosed |