Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25839081 | 0.83 | GABRA1 (0.37) | CES2CES1GABRA1GABRB1 | |
| SCHEMBL23526123 | 0.79 | PDE2A (0.35) | GAAPDE2A | |
| SCHEMBL30014342 | 0.79 | PDE2A (0.35) | GAAPDE2A | |
| SCHEMBL23526125 | 0.79 | PDE2A (0.35) | GAAPDE2A | |
| SCHEMBL2001602 | 0.78 | CES2 (0.52) | CES2CES1PDE2A | |
| SCHEMBL4099522 | 0.78 | CES2 (0.52) | CES2CES1PDE2A | |
| SCHEMBL4101136 | 0.78 | CES2 (0.52) | CES2CES1PDE2A | |
| SCHEMBL24458099 | 0.77 | CES2 (0.34) | CES2CES1PDE2A | |
| SCHEMBL6744704 | 0.75 | CES2 (0.37) | CES2CES1PDE2AGABRA1GABRB1 | |
| SCHEMBL6742156 | 0.75 | CES2 (0.37) | CES2CES1PDE2AGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224001-B1 | ANTHRANILONITRILE DERIVATIVES AND RELATED COMPOUNDS AS USEFUL AGENTS FOR PROMOTING GROWTH, IMPROVING FEED EFFICIENCY, AND FOR INCREASING THE LEAN MEAT TO FAT RATIO OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4863959-A | Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0224001-A1 | Anthranilonitrile derivatives and related compounds as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1987-06-03 | — | — | EP | disclosed |