Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.42 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
| ▸ | GNG2 | P59768 | 1/20 | 0.34 |
| ▸ | GNB1 | P62873 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720129 | 0.80 | GSK3B (0.54) | GSK3BPTPN1VNN1 | |
| SCHEMBL29896949 | 0.80 | GSK3B (0.54) | GSK3BPTPN1VNN1 | |
| SCHEMBL11313120 | 0.77 | ABCC9 (0.43) | GSK3BPTPN1ABCC9ABCC8KCNJ11 | |
| SCHEMBL5165644 | 0.76 | GSK3B (0.54) | GSK3BPTPN1GNG2GNB1ALDH1A1 | |
| SCHEMBL393951 | 0.76 | GSK3B (0.54) | GSK3BPTPN1 | |
| SCHEMBL29896948 | 0.76 | GSK3B (0.54) | GSK3BPTPN1GNG2GNB1ALDH1A1 | |
| SCHEMBL11320230 | 0.75 | ALDH1A1 (0.44) | GSK3BPTPN1ABCC9ABCC8KCNJ11 | |
| SCHEMBL1303698 | 0.73 | GSK3B (0.54) | GSK3BPTPN1 | |
| SCHEMBL30341810 | 0.73 | GSK3B (0.54) | GSK3BPTPN1GNG2GNB1ALDH1A1 | |
| SCHEMBL30622639 | 0.73 | ALDH1A1 (0.51) | GSK3BALDH1A1HPGDVNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224001-B1 | ANTHRANILONITRILE DERIVATIVES AND RELATED COMPOUNDS AS USEFUL AGENTS FOR PROMOTING GROWTH, IMPROVING FEED EFFICIENCY, AND FOR INCREASING THE LEAN MEAT TO FAT RATIO OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4863959-A | Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1989-09-05 | — | — | US | disclosed |