Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820959 | 0.81 | GSK3B (0.40) | GSK3BPTPN1HPGDS | |
| SCHEMBL9821241 | 0.79 | TSHR (0.35) | GSK3BKEAP1 | |
| SCHEMBL14720211 | 0.72 | GSK3B (0.40) | GSK3BPTPN1HPGDS | |
| SCHEMBL20819623 | 0.71 | PTPN1 (0.41) | GSK3BPTPN1HPGDS | |
| SCHEMBL21811303 | 0.69 | IL4 (0.38) | — | |
| SCHEMBL660639 | 0.69 | KDM1A (0.32) | — | |
| SCHEMBL29196717 | 0.68 | TRPV4 (0.37) | — | |
| SCHEMBL19434334 | 0.68 | GSK3B (0.54) | GSK3BPTPN1 | |
| SCHEMBL30195093 | 0.68 | PTPN1 (0.46) | GSK3BPTPN1 | |
| SCHEMBL16082919 | 0.68 | PTPN1 (0.46) | GSK3BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224001-B1 | ANTHRANILONITRILE DERIVATIVES AND RELATED COMPOUNDS AS USEFUL AGENTS FOR PROMOTING GROWTH, IMPROVING FEED EFFICIENCY, AND FOR INCREASING THE LEAN MEAT TO FAT RATIO OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4863959-A | Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0224001-A1 | Anthranilonitrile derivatives and related compounds as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1987-06-03 | — | — | EP | disclosed |