Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821276 | 0.76 | MEN1 (0.54) | TP53HSD17B10KDM4ERAB9AMEN1 | |
| SCHEMBL29952587 | 0.69 | HSD17B10 (0.71) | TP53HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL6654332 | 0.69 | HSD17B10 (1.00) | TP53HSD17B10KDM4ERAB9AMEN1 | |
| SCHEMBL20669783 | 0.67 | PDE10A (0.77) | TP53HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL3089574 | 0.67 | MEN1 (0.52) | KDM4EMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL30079692 | 0.67 | MAPT (0.75) | TP53HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL2822088 | 0.67 | MAPT (0.75) | TP53HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL15487702 | 0.66 | HSD17B10 (0.66) | TP53HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL12220557 | 0.64 | HSD17B10 (0.62) | TP53HSD17B10KDM4ERAB9AMEN1 | |
| SCHEMBL9821213 | 0.64 | HTT (0.52) | TP53HSD17B10KDM4ERAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4789678-A | Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-12-06 | — | — | US | claimed |
| EP-0258755-B1 | ALPHA-ALKYL-4-AMINO-3-QUINOLINE-METHANOLS AND 1-(4-ARALKYLAMINO-3-QUINOLINYL) ALKANONES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-09-11 | — | — | EP | disclosed |
| US-4840972-A | Relief from memory dysfunction with α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-06-20 | — | — | US | disclosed |
| US-4789678-A | Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-12-06 | — | — | US | disclosed |
| EP-0258755-A1 | Alpha-alkyl-4-amino-3-quinoline-methanols and 1-(4-aralkylamino-3-quinolinyl) alkanones, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-03-09 | — | — | EP | disclosed |