Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653554 | 0.87 | ALDH1A1 (0.49) | MEN1KMT2ASMN1; SMN2KDM4ERAB9A | |
| SCHEMBL9821131 | 0.84 | KMT2A (0.59) | MEN1KMT2ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL9821213 | 0.83 | HTT (0.52) | MEN1KMT2ASMN1; SMN2KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL9821072 | 0.83 | KMT2A (0.57) | MEN1KMT2ASMN1; SMN2KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL10567928 | 0.82 | KMT2A (0.53) | MEN1KMT2ASMN1; SMN2KDM4ERAB9A | |
| SCHEMBL7647477 | 0.80 | TP53 (0.45) | MEN1KMT2ASMN1; SMN2KDM4ERAB9A | |
| SCHEMBL6650864 | 0.79 | TP53 (0.51) | MEN1KMT2ASMN1; SMN2TP53HSD17B10 | |
| SCHEMBL6658584 | 0.79 | HSD17B10 (0.51) | MEN1KMT2ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL6652248 | 0.78 | ALDH1A1 (0.49) | MEN1KMT2ASMN1; SMN2TP53HSD17B10 | |
| SCHEMBL9821157 | 0.76 | TP53 (0.51) | MEN1KMT2ASMN1; SMN2KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4789678-A | Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-12-06 | — | — | US | claimed |
| EP-0258755-B1 | ALPHA-ALKYL-4-AMINO-3-QUINOLINE-METHANOLS AND 1-(4-ARALKYLAMINO-3-QUINOLINYL) ALKANONES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-09-11 | — | — | EP | disclosed |
| US-4840972-A | Relief from memory dysfunction with α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-06-20 | — | — | US | disclosed |
| US-4789678-A | Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-12-06 | — | — | US | disclosed |
| EP-0258755-A1 | Alpha-alkyl-4-amino-3-quinoline-methanols and 1-(4-aralkylamino-3-quinolinyl) alkanones, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-03-09 | — | — | EP | disclosed |