Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 10/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.42 |
| ▸ | CTSD | P07339 | 3/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821712 | 1.00 | LTB4R (0.42) | LTB4RLTB4R2CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL9821708 | 1.00 | LTB4R (0.42) | LTB4RLTB4R2CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL9821820 | 0.93 | LTB4R (0.44) | LTB4RLTB4R2CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL9821690 | 0.93 | LTB4R (0.44) | LTB4RLTB4R2CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL9821686 | 0.93 | LTB4R (0.44) | LTB4RLTB4R2CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL9821665 | 0.92 | LTB4R (0.50) | LTB4RLTB4R2CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL9821795 | 0.91 | PPARG (0.44) | LTB4RLTB4R2CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL9821787 | 0.91 | PPARG (0.44) | LTB4RLTB4R2CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL9821791 | 0.91 | PPARG (0.44) | LTB4RLTB4R2CTSDCYSLTR2CYSLTR1 | |
| SCHEMBL9821770 | 0.91 | LTB4R (0.42) | LTB4RLTB4R2CTSDCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292977-B1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLATE DERIVATIVES | G.D. Searle & Co. (US) | 1991-09-04 | — | — | EP | disclosed |
| EP-0292977-A1 | Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives | G.D. Searle & Co. (US) | 1988-11-30 | — | — | EP | disclosed |