SCHEMBL982183

SCHEMBL982183

Oc1cccc(Oc2ccccc2)c1Oc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
HPGD P15428 1/20 0.47
TTR P02766 2/20 0.46
LTA4H P09960 2/20 0.45
NR1H2 P55055 1/20 0.45
BAX Q07812 1/20 0.45
CTNNB1 P35222 1/20 0.44
TSHR P16473 2/20 0.44
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 1/20 0.42
DPP4 P27487 1/20 0.42
KDM4E B2RXH2 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HRH1 P35367 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1834612 0.87 LTA4H (0.52) ALDH1A1HPGDTTRLTA4HNR1H2
SCHEMBL8954581 0.86 CA1 (0.55) ALDH1A1HPGDTTRLTA4HTSHR
SCHEMBL980808 0.85 ALDH1A1 (0.42) ALDH1A1HPGDTTRLTA4HNR1H2
SCHEMBL9780873 0.84 LTA4H (0.55) ALDH1A1HPGDLTA4HNR1H2BAX
SCHEMBL982234 0.83 TTR (0.50) ALDH1A1HPGDTTRLTA4HNR1H2
SCHEMBL396882 0.83 ALDH1A1 (0.52) ALDH1A1HPGDTTRLTA4HNR1H2
SCHEMBL9273369 0.82 TSHR (0.52) ALDH1A1HPGDLTA4HNR1H2BAX
SCHEMBL29449754 0.82 TTR (0.57) ALDH1A1HPGDTTRLTA4HNR1H2
SCHEMBL260447 0.82 TTR (0.57) ALDH1A1HPGDTTRLTA4HNR1H2
SCHEMBL28757850 0.82 LTA4H (0.50) ALDH1A1LTA4HGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1266924-B1 Polycarbonates and polyestercarbonates having branched endgroups BAYER MATERIALSCIENCE AG (DE) 2006-06-28 EP claimed
EP-1266924-A2 Polycarbonates, polyestercarbonates and polyesters having branched endgroups BAYER AG (DE) 2002-12-18 EP claimed
US-5219477-A Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid THE DOW CHEMICAL COMPANY (US) 1993-06-15 US claimed
EP-2275405-B1 PROCESS FOR PRODUCING ISOCYANATE USING DIARYL CARBONATE ASAHI CHEMICAL IND (JP) 2019-04-24 EP disclosed
EP-2275406-B1 PROCESS FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2018-11-28 EP disclosed
EP-3153499-B1 METHOD FOR PRODUCING N-SUBSTITUTED CARBAMIC ACID ESTER ASAHI CHEMICAL IND (JP) 2018-09-19 EP disclosed
EP-2792673-B1 Carbamic acid ester derivatives for the production of isocyanate and aromatic hydroxy compounds ASAHI CHEMICAL IND (JP) 2018-07-25 EP disclosed
EP-2322504-B9 PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER ASAHI CHEMICAL IND (JP) 2017-09-06 EP disclosed
US-9637445-B2 Isocyanate production process using composition containing carbamic acid ester and aromatic hydroxy compound, and composition for transfer and storage of carbamic acid ester ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-05-02 US disclosed
EP-3153500-A1 METHOD FOR PRODUCING ISOCYANATE USING N-SUBSTITUTED CARBAMIC ACID ESTER, AND COMPOSITION FOR TRANSFERRING AND STORING N-SUBSTITUTED CARBAMIC ACID ESTER CONTAINING N-SUBSTITUTED CARBAMIC ACID ESTER AND AROMATIC HYDROXY COMPOUND ASAHI KASEI KABUSHIKI KAISHA (JP) 2017-04-12 EP disclosed
EP-3153499-A1 METHOD FOR PRODUCING N-SUBSTITUTED CARBAMIC ACID ESTER ASAHI KASEI KABUSHIKI KAISHA (JP) 2017-04-12 EP disclosed
EP-1266924-A2 Polycarbonates, polyestercarbonates and polyesters having branched endgroups BAYER AG (DE) 2002-12-18 EP disclosed
EP-1266924-A2 Polycarbonates, polyestercarbonates and polyesters having branched endgroups BAYER AG (DE) 2002-12-18 EP disclosed
US-5710334-A PENDANT ETHER GROUPS, POLYIMIDES WITH IMPROVED SOLUBILITY, MELT FLOW STABILITY, PROCESSABILITY MITSUI TOATSU CHEMICALS, INC. (JP) 1998-01-20 US disclosed
EP-0572196-B1 Polyimide, and preparation process of same MITSUI TOATSU CHEMICALS (JP) 1997-08-06 EP disclosed
US-5480965-A BASED ON A NOVEL DIAMINO COMPOUND DERIVED FROM BENZOPHENONE STRUCTURE; FIBER REINFORCEMENT MITSUI TOATSU CHEMICALS, INC. (JP) 1996-01-02 US disclosed
US-5464569-A In situ formation of alkali metal oxalates in polyphenylene ether basestock MONSANTO COMPANY (US) 1995-11-07 US disclosed
US-5439614-A Colloidal dispersion of aromatic ether and oxidation inhibiting amount of alkali metal salt of oxalic acid MONSANTO COMPANY (US) 1995-08-08 US disclosed
EP-0572196-A1 Polyimide, and preparation process of same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-12-01 EP disclosed
US-5219477-A Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid THE DOW CHEMICAL COMPANY (US) 1993-06-15 US disclosed