Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860050 | 0.83 | ALDH1A1 (0.43) | HDAC6HDAC1ALDH1A1GLANPC1 | |
| SCHEMBL219829 | 0.80 | ALDH1A1 (0.47) | HDAC6HDAC1LTB4R2ALDH1A1GLA | |
| SCHEMBL4153727 | 0.78 | ALDH1A1 (0.63) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL8555208 | 0.78 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9APAX8SMN1; SMN2 | |
| SCHEMBL5967066 | 0.77 | HDAC1 (0.48) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL9366543 | 0.77 | SMN1; SMN2 (0.56) | HDAC6HDAC1TRPM8CNR2LTB4R2 | |
| SCHEMBL16125599 | 0.76 | HDAC1 (0.60) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL9295793 | 0.76 | TP53 (0.62) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL60236 | 0.75 | MEN1 (0.65) | HDAC6HDAC8CNR2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6208128 | 0.74 | MEN1 (0.63) | HDAC6HDAC8CNR2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194464-B1 | AMINO ACID DERIVATIVES AND USE THEREOF FOR THE PREPARATION OF AN ANTICONVULSANT | Research Corporation Technologies, Inc. (a Delaware corp.) (US) | 1991-04-03 | — | — | EP | disclosed |