Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | VEGFA | P15692 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11667796 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL8860050 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL690247 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL11557648 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL9821895 | 0.80 | HDAC6 (0.57) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL464919 | 0.80 | HDAC1 (0.57) | ALDH1A1GLAKMT2AMEN1L3MBTL1 | |
| SCHEMBL10536986 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL10539922 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL7505138 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRGLAKMT2AMEN1 | |
| SCHEMBL5353769 | 0.79 | ALDH1A1 (0.51) | ALDH1A1TSHRGLAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486917-B1 | COATING FILM, AND GRANULES AND TABLETS EACH UTILIZING SAME | ASAHI CHEMICAL IND (JP) | 2020-11-25 | — | — | EP | disclosed |
| EP-2050438-B1 | SPHERICAL CRUDE GRANULE AND METHOD FOR PRODUCTION THEREOF | ASAHI CHEMICAL IND (JP) | 2016-10-19 | — | — | EP | disclosed |
| US-9439865-B2 | Coating film, and granules and tablets each utilizing same | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-09-13 | — | — | US | disclosed |
| US-20150104513-A1 | COATING FILM, AND GRANULES AND TABLETS EACH UTILIZING SAME | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-04-16 | — | — | US | disclosed |
| US-8992988-B2 | Coating film, and granules and tablets each utilizing same | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8765187-B2 | Aqueous composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2014-07-01 | — | — | US | disclosed |
| EP-1981487-B1 | LATEX OR PSEUDOLATEX COMPOSITIONS COATINGS AND COATING PROCESSES | FMC CORP (US) | 2014-06-25 | — | — | EP | disclosed |
| EP-2486917-A1 | COATING FILM, AND GRANULES AND TABLETS EACH UTILIZING SAME | Asahi Kasei Chemicals Corporation (JP) | 2012-08-15 | — | — | EP | disclosed |
| US-20120189696-A1 | COATING FILM, AND GRANULES AND TABLETS EACH UTILIZING SAME | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2012-07-26 | — | — | US | disclosed |
| US-8088414-B2 | Latex or pseudolatex compositions, coatings and coating processes | FMC CORPORATION (US) | 2012-01-03 | — | — | US | disclosed |
| US-20040236107-A1 | Intermediate compounds for the preparation of mirtazapine and the production methods thereof | MEDICHEM, S.A. (ES) | 2004-11-25 | — | — | US | disclosed |
| EP-1426356-A1 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF MIRTAZAPINE AND THE PRODUCTION METHODS THEREOF | Medichem S.A. (ES) | 2004-06-09 | — | — | EP | disclosed |
| EP-0400440-B1 | Amino acid derivative anticonvulsant | RES CORP TECHNOLOGIES INC (US) | 2002-03-13 | — | — | EP | disclosed |
| US-5654301-A | Lacosamide FDA Orange book listed patent | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-08-05 | — | — | US | disclosed |
| US-5378729-A | Diamide derivatives | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-01-03 | — | — | US | disclosed |
| WO-1992021648-A1 | AMINO ACID DERIVATIVE ANTICONVULSANT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-12-10 | — | — | WO | disclosed |
| EP-0194464-B1 | AMINO ACID DERIVATIVES AND USE THEREOF FOR THE PREPARATION OF AN ANTICONVULSANT | Research Corporation Technologies, Inc. (a Delaware corp.) (US) | 1991-04-03 | — | — | EP | disclosed |
| WO-1990015069-A2 | AMINO ACID DERIVATIVE ANTICONVULSANT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-13 | — | — | WO | disclosed |
| EP-0400440-A1 | Amino acid derivative anticonvulsant | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0194464-A1 | Amino acid derivatives and use thereof for the preparation of an anticonvulsant | Research Corporation Technologies, Inc. (a Delaware corp.) (US) | 1986-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236107-A1 | Intermediate compounds for the preparation of mirtazapine and the production methods thereof | IMPDH1, MRM1, IMPDH2 | ALDH1A1 694/4885TSHR 3450/4885GLA 1931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.