Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | BLM | P54132 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL6385362 | 1.00 | CA5A (0.43) | CA5ACA5BTSHRTP53GAPDH | |
| Sulfuric Acid SCHEMBL6385517 | 1.00 | CA5A (0.43) | CA5ACA5BTSHRTP53GAPDH | |
| Sulfuric Acid SCHEMBL525600 | 0.97 | CA5A (0.40) | CA5ACA5BTSHRTP53GAPDH | |
| SCHEMBL7758306 | 0.90 | TSHR (0.39) | CA5ACA5BTSHRTP53GAPDH | |
| SCHEMBL7704582 | 0.90 | TSHR (0.39) | CA5ACA5BTSHRTP53GAPDH | |
| Sulfamate SCHEMBL8822931 | 0.87 | CA1 (0.50) | CA5ACA5BTSHRTP53HSD17B10 | |
| Butanol SCHEMBL18427897 | 0.83 | TSHR (0.67) | CA5ACA5BTSHRTP53GAPDH | |
| SCHEMBL8594259 | 0.82 | TSHR (0.35) | TSHR | |
| SCHEMBL14994799 | 0.80 | TSHR (0.58) | TSHRGAPDHKDM4E | |
| SCHEMBL16959 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3005452-A | — | — | None | — | — | JP | disclosed |
| CN-119119119-A | Water-soluble polyketone catalyst ligand and synthesis method thereof | 黄河三角洲京博化工研究院有限公司 | 2024-12-13 | — | — | CN | disclosed |
| JP-H035452-A | PREPARATION OF AROMATIC ETHER | RHONE POULENC SANTE | 1991-01-11 | — | — | JP | disclosed |