SCHEMBL9821963

SCHEMBL9821963

COc1nc2nc(COC(C)=O)nn2c(O)c1C=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10588034 0.76 KDM4E (0.35) KDM4E
SCHEMBL9822108 0.69 KDM4E (0.40) KDM4E
SCHEMBL9821957 0.68 KDM4E (0.37) KDM4E
SCHEMBL9822154 0.65 KDM4E (0.39) KDM4E
SCHEMBL9142310 0.64 KDM4E (0.36) KDM4E
SCHEMBL9142508 0.64 KDM4E (0.36) KDM4E
SCHEMBL9822141 0.64 KDM4E (0.50) KDM4E
SCHEMBL9564745 0.63 KDM4E (0.35) KDM4E
SCHEMBL9821955 0.56 TP53 (0.42) KDM4E
SCHEMBL14434339 0.56 ALDH1A1 (0.39) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4987129-A BACTERICIDES SANKEI PHARMACEUTICAL CO., LTD. (JP) 1991-01-22 US disclosed
EP-0302633-A2 Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) 1989-02-08 EP disclosed