Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822134 | 0.87 | RECQL (0.40) | RECQLALDH1A1HTTPDE10AKDM4E | |
| SCHEMBL9821980 | 0.81 | RECQL (0.36) | RECQLALDH1A1HTTPDE10AKDM4E | |
| SCHEMBL9822120 | 0.80 | PKM (0.38) | RECQLALDH1A1HTTPDE10APKM | |
| SCHEMBL10910540 | 0.72 | KDM4E (0.36) | RECQLALDH1A1HTTKDM4ENPSR1 | |
| SCHEMBL9822174 | 0.71 | RECQL (0.53) | RECQLALDH1A1HTTPDE10AKDM4E | |
| SCHEMBL10407055 | 0.71 | MEN1 (0.48) | ALDH1A1PDE10AKDM4ENPSR1 | |
| SCHEMBL10582991 | 0.69 | KDM4E (0.36) | RECQLALDH1A1HTTKDM4ENPSR1 | |
| SCHEMBL13404830 | 0.68 | KDM4E (0.48) | RECQLALDH1A1HTTKDM4E | |
| SCHEMBL9822171 | 0.68 | PKM (0.35) | RECQLALDH1A1KDM4ENPSR1PKM | |
| SCHEMBL9822140 | 0.68 | RECQL (0.41) | RECQLALDH1A1HTTPDE10AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0302633-A2 | Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-02-08 | — | — | EP | disclosed |