Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822487 | 0.83 | KDM4E (0.35) | LMNAKDM4EL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL9142261 | 0.83 | POLB (0.33) | KDM4EPOLB | |
| SCHEMBL9822062 | 0.82 | LMNA (0.35) | LMNAKDM4EL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL9821989 | 0.76 | RECQL (0.35) | KDM4EALDH1A1RECQL | |
| SCHEMBL9300412 | 0.75 | RECQL (0.53) | KDM4EALDH1A1RECQLPOLB | |
| SCHEMBL10407057 | 0.73 | KDM4E (0.38) | KDM4EALDH1A1RECQLHPGDPOLB | |
| SCHEMBL9822121 | 0.73 | RECQL (0.33) | ALDH1A1RECQL | |
| SCHEMBL9822398 | 0.72 | ALDH1A1 (0.34) | KDM4EALDH1A1RECQLHPGDMAPT | |
| SCHEMBL9822341 | 0.71 | ALDH1A1 (0.37) | LMNAKDM4EALDH1A1CLK4POLB | |
| SCHEMBL9822234 | 0.70 | HCAR2 (0.39) | LMNAKDM4EALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |