Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822120 | 0.82 | PKM (0.38) | PKMRECQLALDH1A1PDE10AHTT | |
| SCHEMBL9821980 | 0.79 | RECQL (0.36) | PKMRECQLALDH1A1PDE10AHTT | |
| SCHEMBL9822140 | 0.77 | RECQL (0.41) | PKMRECQLALDH1A1PDE10AHTT | |
| SCHEMBL9821928 | 0.74 | RECQL (0.50) | RECQLALDH1A1PDE10AHTTKDM4E | |
| SCHEMBL9822255 | 0.71 | LMNA (0.33) | PKMRECQLALDH1A1HTT | |
| SCHEMBL9822104 | 0.71 | PKM (0.36) | PKM | |
| SCHEMBL9822056 | 0.68 | PDE10A (0.36) | PKMRECQLALDH1A1PDE10AHTT | |
| SCHEMBL9822045 | 0.68 | TDP1 (0.33) | PKMRECQLALDH1A1HTT | |
| SCHEMBL9822209 | 0.68 | RECQL (0.50) | RECQLALDH1A1PDE10AHTTKDM4E | |
| SCHEMBL9822314 | 0.68 | RECQL (0.50) | PKMRECQLALDH1A1PDE10AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0302633-A2 | Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-02-08 | — | — | EP | disclosed |