Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | SORD | Q00796 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770445 | 0.82 | KMT2A (0.38) | KMT2AMEN1RECQLALDH1A1HTT | |
| SCHEMBL9822064 | 0.81 | KMT2A (0.37) | KMT2AMEN1RECQLALDH1A1HTT | |
| SCHEMBL10414519 | 0.79 | SORD (0.38) | KMT2AMEN1ALDH1A1SMN1; SMN2SORD | |
| SCHEMBL9822357 | 0.79 | — | — | |
| SCHEMBL9822245 | 0.79 | MEN1 (0.34) | KMT2AMEN1TSHR | |
| SCHEMBL9822261 | 0.75 | SORD (0.36) | SORD | |
| SCHEMBL10407053 | 0.72 | KMT2A (0.63) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9822174 | 0.72 | RECQL (0.53) | KMT2ARECQLALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9770272 | 0.70 | KMT2A (0.39) | KMT2AMEN1RECQLALDH1A1HTT | |
| SCHEMBL1681579 | 0.70 | KMT2A (0.39) | KMT2AMEN1RECQLALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |