Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18208841 | 0.85 | KDM4E (0.62) | KDM4EHSD11B1HSD17B10SMN1; SMN2GAA | |
| SCHEMBL9822205 | 0.84 | KDM4E (0.47) | KDM4EHSD11B1HSD17B10SMN1; SMN2GAA | |
| SCHEMBL19436746 | 0.77 | ALDH1A1 (0.57) | KDM4EHSD17B10SMN1; SMN2TSHRMEN1 | |
| SCHEMBL9300782 | 0.77 | KDM4E (0.71) | KDM4EHSD17B10SMN1; SMN2GAATSHR | |
| SCHEMBL19436621 | 0.76 | ALDH1A1 (0.56) | KDM4EHSD17B10SMN1; SMN2TSHRMEN1 | |
| SCHEMBL19436798 | 0.74 | HSD17B10 (0.54) | KDM4EHSD17B10SMN1; SMN2TSHRMEN1 | |
| SCHEMBL19436667 | 0.74 | HSD17B10 (0.68) | KDM4EHSD17B10SMN1; SMN2GAATSHR | |
| SCHEMBL29929318 | 0.74 | HSD17B10 (0.54) | KDM4EHSD17B10SMN1; SMN2TSHRMEN1 | |
| SCHEMBL18208385 | 0.74 | KDM4E (0.62) | KDM4EHSD11B1HSD17B10SMN1; SMN2GAA | |
| SCHEMBL19436650 | 0.74 | HSD17B10 (0.53) | KDM4EHSD17B10SMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0302633-A2 | Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-02-08 | — | — | EP | disclosed |