SCHEMBL9822126

SCHEMBL9822126

OCc1cc(S)n2ncc(CO)c2n1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9822411 0.82 PDE2A (0.42) PDE2A
SCHEMBL9822142 0.80 PDE2A (0.31) PDE2A
SCHEMBL9822070 0.80 KDM4E (0.48)
SCHEMBL9822013 0.68 PDE10A (0.40)
SCHEMBL10579322 0.68 ALDH1A1 (0.40)
SCHEMBL9822430 0.66 PDE2A (0.42) PDE2A
SCHEMBL9822243 0.64 TP53 (0.33)
SCHEMBL9821989 0.64 RECQL (0.35)
SCHEMBL9822180 0.63 KDM4E (0.37)
SCHEMBL3898819 0.62 PDE2A (0.33) PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4987129-A BACTERICIDES SANKEI PHARMACEUTICAL CO., LTD. (JP) 1991-01-22 US disclosed
US-4958019-A Intermediates for synthesis of cephalosporin compounds SANKEI PHARMACEUTICAL CO., LTD. (JP) 1990-09-18 US disclosed
US-4956462-A Bactericides, ANTIBIOTICS, CEPHALOSPORINS SANKEI PHARMACEUTICAL CO., LTD. (JP) 1990-09-11 US disclosed
EP-0302633-A2 Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) 1989-02-08 EP disclosed