Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822116 | 0.85 | KMT2A (0.38) | KMT2AMEN1KDM4ETP53ALDH1A1 | |
| SCHEMBL1681494 | 0.78 | CKS1B (0.44) | KMT2AMEN1CKS1BSKP2KDM4E | |
| SCHEMBL9822141 | 0.72 | KDM4E (0.50) | KMT2ACKS1BSKP2KDM4ETP53 | |
| SCHEMBL9680203 | 0.71 | DPP4 (0.48) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL13729553 | 0.69 | CKS1B (0.49) | CKS1BSKP2TP53ALDH1A1HPGD | |
| SCHEMBL20266745 | 0.66 | KDM4E (0.78) | KMT2AMEN1KDM4ETP53ALDH1A1 | |
| SCHEMBL10952409 | 0.66 | DPP4 (0.44) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL9678782 | 0.66 | KDM4E (0.60) | CKS1BSKP2KDM4ETP53ALDH1A1 | |
| SCHEMBL18373030 | 0.65 | RECQL (0.53) | CKS1BSKP2KDM4ETP53ALDH1A1 | |
| SCHEMBL27385291 | 0.65 | POLB (0.38) | KMT2AKDM4ETP53ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0302633-A2 | Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-02-08 | — | — | EP | disclosed |