Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822172 | 0.85 | KMT2A (0.37) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL9770272 | 0.76 | KMT2A (0.39) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL10516889 | 0.73 | KMT2A (0.41) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL9822317 | 0.71 | KDM4E (0.51) | KMT2AALDH1A1HPGDKDM4ETP53 | |
| SCHEMBL4613719 | 0.70 | L3MBTL1 (0.46) | ALDH1A1HPGDTP53L3MBTL1LMNA | |
| SCHEMBL6554113 | 0.70 | KMT2A (0.65) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL9678829 | 0.70 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL9770417 | 0.69 | RECQL (0.46) | KMT2AALDH1A1HPGDKDM4ETP53 | |
| SCHEMBL4612108 | 0.67 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4ERECQLALOX15 | |
| SCHEMBL9678451 | 0.66 | KDM4E (0.55) | KMT2AMEN1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0302633-A2 | Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-02-08 | — | — | EP | disclosed |