Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27532740 | 0.83 | POLB (0.39) | POLBLMNATP53L3MBTL1KMT2A | |
| SCHEMBL27387597 | 0.81 | KDM4E (0.37) | POLBTP53KMT2AMAPTALDH1A1 | |
| SCHEMBL9141671 | 0.74 | L3MBTL1 (0.47) | POLBLMNATP53L3MBTL1ALDH1A1 | |
| SCHEMBL27792580 | 0.72 | KMT2A (0.47) | LMNAKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13729553 | 0.71 | CKS1B (0.49) | POLBLMNATP53L3MBTL1MAPT | |
| SCHEMBL9679448 | 0.71 | ALDH1A1 (0.48) | POLBTP53L3MBTL1ALDH1A1HPGD | |
| SCHEMBL27388298 | 0.68 | MAPK1 (0.35) | POLBLMNATP53L3MBTL1ALDH1A1 | |
| SCHEMBL9143481 | 0.68 | SMN1; SMN2 (0.40) | TP53L3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27625586 | 0.67 | ALDH1A1 (0.50) | POLBLMNAKMT2AMAPTALDH1A1 | |
| SCHEMBL27841722 | 0.67 | LMNA (0.38) | LMNAKMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1072684-A | Cephalosporins derivatives | HOFFMANN LA ROCHE (CH) | 1993-06-02 | — | — | CN | disclosed |