Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822097 | 0.97 | PKM (0.35) | LMNAPKMPOLB | |
| SCHEMBL9822255 | 0.84 | LMNA (0.33) | LMNAPKMHTTRECQLSMN1; SMN2 | |
| SCHEMBL9822104 | 0.82 | PKM (0.36) | LMNAPKMPOLB | |
| SCHEMBL9822417 | 0.81 | LMNA (0.35) | LMNAPKMSMN1; SMN2NPSR1KDM4E | |
| SCHEMBL10397427 | 0.79 | LMNA (0.33) | LMNAPKMHTTRECQLSMN1; SMN2 | |
| SCHEMBL9822171 | 0.78 | PKM (0.35) | LMNAPKMRECQLNPSR1KDM4E | |
| SCHEMBL10408137 | 0.74 | PKM (0.45) | LMNAPKMRECQLNPSR1KDM4E | |
| SCHEMBL9822277 | 0.73 | LMNA (0.39) | LMNAPKMNPSR1KDM4EALDH1A1 | |
| SCHEMBL9822120 | 0.72 | PKM (0.38) | PKMHTTRECQLALDH1A1 | |
| SCHEMBL10698968 | 0.67 | KDM4E (0.36) | LMNAPKMSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |