Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10415953 | 0.84 | KDM4E (0.42) | KDM4EPOLBALDH1A1KMT2ATDP1 | |
| SCHEMBL10407785 | 0.80 | POLB (0.59) | KDM4EPOLBALDH1A1KMT2ATDP1 | |
| SCHEMBL9677476 | 0.77 | KDM4E (0.44) | KDM4EPOLBALDH1A1KMT2ATDP1 | |
| SCHEMBL9822031 | 0.75 | KDM4E (0.41) | KDM4EPOLBALDH1A1KMT2ATDP1 | |
| SCHEMBL9822273 | 0.74 | KDM4E (0.42) | KDM4EPOLBALDH1A1KMT2ATDP1 | |
| SCHEMBL10407369 | 0.72 | ALDH1A1 (0.60) | KDM4EPOLBALDH1A1KMT2ATDP1 | |
| SCHEMBL9822217 | 0.71 | KDM4E (0.40) | KDM4EPOLBALDH1A1KMT2ATDP1 | |
| SCHEMBL9822214 | 0.70 | SORD (0.35) | — | |
| SCHEMBL10407079 | 0.69 | CSNK1D (0.44) | KDM4EPOLBALDH1A1KMT2ATDP1 | |
| SCHEMBL9679451 | 0.69 | KDM4E (0.37) | KDM4EPOLBALDH1A1TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| US-4812501-A | AGAINST OXIDATIVE, THERMAL AND ACTINIC DEGRADATION | CIBA-GEIGY CORPORATION (US) | 1989-03-14 | — | — | US | disclosed |
| EP-0302633-A2 | Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-02-08 | — | — | EP | disclosed |
| US-4751319-A | 1,3,2-oxazaphospholdine stabilizers | CIBA-GEIGY CORPORATION (US) | 1988-06-14 | — | — | US | disclosed |