Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822194 | 0.81 | KDM4E (0.41) | KDM4EHPGDALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL9822180 | 0.81 | KDM4E (0.37) | KDM4EALDH1A1SMN1; SMN2MAOBUSP2 | |
| SCHEMBL9822152 | 0.76 | TDP1 (0.46) | KDM4EHPGDALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL10407427 | 0.76 | PIK3CG (0.44) | KDM4EHPGDALDH1A1SMN1; SMN2MAOB | |
| SCHEMBL9822431 | 0.75 | KDM4E (0.38) | KDM4EHPGDALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL9821940 | 0.75 | KDM4E (0.38) | KDM4EHPGDALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL9822425 | 0.69 | ALDH1A1 (0.40) | KDM4EHPGDALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL9821991 | 0.68 | TDP1 (0.38) | KDM4EHPGDALDH1A1HSD17B10TDP1 | |
| SCHEMBL9822041 | 0.67 | KMT2A (0.44) | KDM4EHPGDALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL10407049 | 0.67 | CYP1A2 (0.39) | KDM4EALDH1A1SMN1; SMN2MAOBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0302633-A2 | Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-02-08 | — | — | EP | disclosed |