Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821991 | 0.81 | TDP1 (0.38) | TDP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9822243 | 0.80 | TP53 (0.33) | ALDH1A1KDM4EMAPTSMN1; SMN2TP53 | |
| SCHEMBL9822041 | 0.80 | KMT2A (0.44) | TDP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9866533 | 0.76 | TDP1 (0.41) | TDP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9822200 | 0.76 | KDM4E (0.41) | TDP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9822425 | 0.76 | ALDH1A1 (0.40) | TDP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9822045 | 0.76 | TDP1 (0.33) | TDP1ALDH1A1PKM | |
| SCHEMBL9142254 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL9821984 | 0.74 | GAA (0.33) | TDP1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL6261617 | 0.73 | ALDH1A1 (0.45) | ALDH1A1HPGDSMN1; SMN2TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987129-A | BACTERICIDES | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4958019-A | Intermediates for synthesis of cephalosporin compounds | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4956462-A | Bactericides, ANTIBIOTICS, CEPHALOSPORINS | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0302633-A2 | Beta-lactam compound, process for preparing the same, intermediate for synthesis of the same and medicinal composition for bacterially infectious disease therapy containing the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-02-08 | — | — | EP | disclosed |