Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.56 |
| ▸ | RARB | P10826 | 5/20 | 0.49 |
| ▸ | RARG | P13631 | 5/20 | 0.49 |
| ▸ | RARA | P10276 | 4/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 7/20 | 0.43 |
| ▸ | CYP26B1 | Q9NR63 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822546 | 0.82 | RXRA (0.64) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL9822401 | 0.81 | RXRA (0.63) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL9822558 | 0.79 | RXRA (0.59) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL9822510 | 0.78 | RARB (0.61) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL7545408 | 0.74 | RARG (0.62) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL7088904 | 0.74 | RARG (0.62) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL9822477 | 0.73 | CYP26A1 (0.53) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL9822473 | 0.73 | CYP26A1 (0.53) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL8458824 | 0.72 | RXRA (1.00) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL10355872 | 0.71 | RXRA (0.54) | RXRARARBRARGRARACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297995-B1 | POLYCYCLIC AROMATIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND ANIMAL MEDICINE AND IN COSMETICS | L'OREAL (FR) | 1991-03-06 | — | — | EP | claimed |