Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.61 |
| ▸ | RARG | P13631 | 11/20 | 0.61 |
| ▸ | RARA | P10276 | 10/20 | 0.61 |
| ▸ | RXRA | P19793 | 3/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822546 | 0.79 | RXRA (0.64) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9822486 | 0.79 | RARB (0.66) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9822401 | 0.78 | RXRA (0.63) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9822469 | 0.78 | RXRA (0.56) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9822527 | 0.77 | CYP26B1 (0.44) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9746456 | 0.77 | RARA (0.63) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9746853 | 0.76 | RARB (0.65) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL6372648 | 0.76 | RARB (1.00) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL8457553 | 0.76 | RARB (0.65) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9747949 | 0.75 | RARB (0.71) | RARBRARGRARARXRACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297995-B1 | POLYCYCLIC AROMATIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND ANIMAL MEDICINE AND IN COSMETICS | L'OREAL (FR) | 1991-03-06 | — | — | EP | claimed |
| US-4980509-A | Aromatic polycyclic derivatives, their process of preparation and their use in human and veterinary medicine and in cosmetics | SOCIETE ANONYME DITE: L'OREAL (FR) | 1990-12-25 | — | — | US | claimed |
| US-4980509-A | Aromatic polycyclic derivatives, their process of preparation and their use in human and veterinary medicine and in cosmetics | SOCIETE ANONYME DITE: L'OREAL (FR) | 1990-12-25 | — | — | US | disclosed |