Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27497610 | 0.86 | CYP2C9 (0.49) | HNF4AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29444101 | 0.84 | ALDH1A1 (0.52) | HNF4AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1815797 | 0.84 | ALDH1A1 (0.52) | HNF4AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5678745 | 0.82 | HNF4A (0.76) | HNF4AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28253167 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10CYP2C9 | |
| SCHEMBL8031425 | 0.80 | HNF4A (0.74) | HNF4AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10948911 | 0.80 | HNF4A (0.73) | HNF4AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1646799 | 0.79 | ALDH1A1 (0.51) | HNF4AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5364053 | 0.79 | CA12 (0.39) | HNF4AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL30259301 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDHSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1285818-A | Compounds for antemortem diagnosis and in vivo imaging of alzheimer's disease and prevention of amyloid deposition | UNIV PITTSBURGH (US) | 2001-02-28 | — | — | CN | disclosed |
| US-5032572-A | Drug delivery | MEDICAL COLLEGE OF OHIO (US) | 1991-07-16 | — | — | US | disclosed |
| US-4663308-A | Method of use of polymers containing cross-linked azo bonds for releasing therapeutic agents into the lower gastrointestinal tract | MEDICAL COLLEGE OF OHIO (US) | 1987-05-05 | — | — | US | disclosed |