Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031428 | 0.82 | ALDH1A1 (0.54) | AKR1C3ALDH1A1ALOX15HTTCTNNB1 | |
| SCHEMBL27831937 | 0.81 | HTT (0.43) | AKR1C3ALDH1A1ALOX15HTTCTNNB1 | |
| SCHEMBL5468604 | 0.80 | ALDH1A1 (0.44) | ALDH1A1ALOX15HTTHPGDGAA | |
| SCHEMBL2987532 | 0.80 | ALDH1A1 (0.40) | ALDH1A1ALOX15HPGDLMNAMAPK1 | |
| SCHEMBL3961138 | 0.77 | KDM4E (0.61) | ALDH1A1ALOX15HPGDLMNAMAPK1 | |
| SCHEMBL3264284 | 0.77 | FOLH1 (0.41) | AKR1C3ALDH1A1HTTCTNNB1GAA | |
| SCHEMBL30259301 | 0.77 | ALDH1A1 (0.56) | AKR1C3ALDH1A1ALOX15HPGDLMNA | |
| SCHEMBL31100 | 0.77 | ALDH1A1 (0.56) | AKR1C3ALDH1A1ALOX15HPGDLMNA | |
| Benzene SCHEMBL28254104 | 0.77 | ALDH1A1 (0.56) | AKR1C3ALDH1A1ALOX15HPGDLMNA | |
| SCHEMBL7616228 | 0.76 | HSD17B10 (0.41) | ALDH1A1ALOX15HTTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032572-A | Drug delivery | MEDICAL COLLEGE OF OHIO (US) | 1991-07-16 | — | — | US | disclosed |
| US-4663308-A | Method of use of polymers containing cross-linked azo bonds for releasing therapeutic agents into the lower gastrointestinal tract | MEDICAL COLLEGE OF OHIO (US) | 1987-05-05 | — | — | US | disclosed |