SCHEMBL5468604

SCHEMBL5468604

C=Cc1cccc(C(=O)O)c1OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 2/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
MAPK1 P28482 1/20 0.44
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
APEX1 P27695 4/20 0.42
NFE2L2 Q16236 2/20 0.41
MAPT P10636 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HTT P42858 1/20 0.41
TLR2 O60603 1/20 0.41
TLR1 Q15399 1/20 0.41
TLR6 Q9Y2C9 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
GAA P10253 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2949035 0.85 LMNA (0.44) ALDH1A1KDM4EHPGDHSD17B10CA1
SCHEMBL3961138 0.83 KDM4E (0.61) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL31617875 0.83 BACE1 (0.41) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL2987532 0.83 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL16957047 0.82 CA1 (0.41) ALDH1A1KDM4EHPGDCA1CA2
SCHEMBL7616228 0.82 HSD17B10 (0.41) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL39857 0.81 ALDH1A1 (0.55) ALDH1A1KDM4EHPGDHSD17B10MAPK1
Methoxymethane SCHEMBL6152425 0.80 ALDH1A1 (0.48) ALDH1A1KDM4EHPGDHSD17B10CA1
SCHEMBL9822684 0.80 AKR1C3 (0.41) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL2409607 0.80 CA1 (0.37) ALDH1A1KDM4EHPGDHSD17B10CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090023928-A1 PHTHALAMIDE-LANTHANIDE COMPLEXES FOR USE AS LUMINESCENT MARKERS THE REGENTS OF THE UNIVERISTY OF CALIFORNIA (US) 2009-01-22 US disclosed
US-7247697-B2 Coating compositions for use in golf balls ACUSHNET COMPANY (US) 2007-07-24 US disclosed
US-20060089419-A1 Coating compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2006-04-27 US disclosed
US-4097352-A PROTECTIVE COATINGS FOR CATHODES PPG INDUSTRIES, INC. (US) 1978-06-27 US disclosed
US-4066592-A ZWITTERION-CONTAINING COMPOSITIONS PPG INDUSTRIES, INC. (US) 1978-01-03 US disclosed
US-4038232-A YELLOWING RESISTANCE PPG INDUSTRIES, INC. (US) 1977-07-26 US disclosed
US-4038166-A ELECTROCOATING, SYNTHETIC ORGANIC RESINS, AMINE-ALDEHYDE CONDENSATE PPG INDUSTRIES, INC. (US) 1977-07-26 US disclosed
US-4035275-A ELECTRODEPOSITION, CATIONIC EPOXY RESINS PPG INDUSTRIES, INC. (US) 1977-07-12 US disclosed
US-4031290-A ALPHA-BETA MONOMERS, CATALYSIS PPG INDUSTRIES, INC. (US) 1977-06-21 US disclosed
US-4016332-A OF ETHYLENICALLY UNSATURATED MONOMERS PPG INDUSTRIES, INC. (US) 1977-04-05 US disclosed
US-4001156-A Method of producing epoxy group-containing, quaternary ammonium salt-containing resins PPG INDUSTRIES, INC. (US) 1977-01-04 US disclosed
US-3975346-A ELECTRO-DEPOSITION PPG INDUSTRIES, INC. (US) 1976-08-17 US disclosed
US-3959106-A EPOXY COMPOUNDS; SULFIDES PPG INDUSTRIES, INC. (US) 1976-05-25 US disclosed
US-3937679-A COATINGS, AMMONIUM, SULFONIUM, OR PHOSPHONIUM ACID SALT, AMINE-ALDEHYDE CONDENSATE, AND A METHYOL PHENOL ETHER PPG INDUSTRIES, INC. (US) 1976-02-10 US disclosed
US-3936405-A CATIONIC POLYMER PPG INDUSTRIES, INC. (US) 1976-02-03 US disclosed
US-3933940-A Mercaptan blocked thermosetting copolymers PPG INDUSTRIES, INC. (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090023928-A1 PHTHALAMIDE-LANTHANIDE COMPLEXES FOR USE AS LUMINESCENT MARKERS PIN4, PIN1, SLC39A14 ALDH1A1 2715/4885KDM4E 2382/4885HPGD 2844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.