Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822814 | 0.96 | HTR3A (0.37) | HTR3ASSTR4 | |
| Fumaric Acid SCHEMBL9866830 | 0.91 | HTR3A (0.35) | HTR3ASSTR4 | |
| Fumaric Acid SCHEMBL9866819 | 0.91 | HTR3A (0.35) | HTR3ASSTR4 | |
| SCHEMBL9822700 | 0.87 | PARP1 (0.32) | — | |
| SCHEMBL9822687 | 0.82 | CNR1 (0.30) | — | |
| SCHEMBL9822832 | 0.82 | — | — | |
| SCHEMBL10368616 | 0.77 | — | — | |
| SCHEMBL9822894 | 0.74 | PARP1 (0.30) | — | |
| SCHEMBL9822741 | 0.72 | — | — | |
| SCHEMBL9822989 | 0.72 | HTR3A (0.42) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231139-B1 | DIHYDROBENZOFURANE AND CHROMANE CARBOXAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS NEUROLEPTICS | Laboratoires DELAGRANGE (FR) | 1991-12-04 | — | — | EP | claimed |
| US-5006570-A | Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics | LABORATOIRES DELAGRANGE (FR) | 1991-04-09 | — | — | US | claimed |
| US-5006570-A | Dihydrobenzofuran- and chroman-carboxamide derivatives, processes for the preparation thereof and use thereof as neuroleptics | LABORATOIRES DELAGRANGE (FR) | 1991-04-09 | — | — | US | disclosed |