Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392318 | 0.89 | TSHR (0.59) | TSHRKMT2AL3MBTL1SMN1; SMN2HTT | |
| SCHEMBL5158837 | 0.87 | TSHR (0.53) | TSHRKMT2AL3MBTL1SMN1; SMN2HTT | |
| SCHEMBL7979583 | 0.83 | TSHR (0.53) | TSHRKMT2AL3MBTL1SMN1; SMN2HTT | |
| SCHEMBL11494953 | 0.82 | TSHR (0.46) | TSHRKMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL9708708 | 0.81 | GSK3A (0.49) | TSHRKMT2AAOC3ALDH1A1LMNA | |
| SCHEMBL11165685 | 0.78 | TSHR (0.40) | TSHRKMT2AL3MBTL1SMN1; SMN2HTT | |
| SCHEMBL11315834 | 0.77 | — | — | |
| SCHEMBL24879866 | 0.77 | SMN1; SMN2 (0.41) | TSHRKMT2AL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL532516 | 0.77 | L3MBTL1 (0.37) | TSHRKMT2AL3MBTL1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL17396676 | 0.75 | L3MBTL1 (0.36) | TSHRKMT2AL3MBTL1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58198492-A | — | — | None | — | — | JP | disclosed |
| EP-0365212-A3 | Method of resolving cis 3-amino-4-[2-(2-furyl)eth-1-YL]-1-methoxycarbonylmethyl-azetidin-2-one and malic acid salts thereof | ELI LILLY AND COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0416736-A2 | Method of resolving cis 3-amino-4-[2-(2-furyl)eth-1-yl]-1-methoxycarbonylmethyl-azetidin-2-one | ELI LILLY AND COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0416736-A2 | Method of resolving cis 3-amino-4-[2-(2-furyl)eth-1-yl]-1-methoxycarbonylmethyl-azetidin-2-one | ELI LILLY AND COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0365213-A2 | Method of resolving cis 3-amino-4-[2-(2-furyl)vinyl]-1-methoxy-carbonylmethyl-azetidin-2-one and di-p-toluoyl-tartaric acid salts thereof | ELI LILLY AND COMPANY (US) | 1990-04-25 | — | — | EP | disclosed |
| EP-0365212-A2 | Method of resolving cis 3-amino-4-[2-(2-furyl)eth-1-YL]-1-methoxycarbonylmethyl-azetidin-2-one and malic acid salts thereof | ELI LILLY AND COMPANY (US) | 1990-04-25 | — | — | EP | disclosed |
| EP-0365212-A2 | Method of resolving cis 3-amino-4-[2-(2-furyl)eth-1-YL]-1-methoxycarbonylmethyl-azetidin-2-one and malic acid salts thereof | ELI LILLY AND COMPANY (US) | 1990-04-25 | — | — | EP | disclosed |
| JP-S58198492-A | NOVEL AZETIDINE DERIVATIVE AND ITS PREPARATION | KOWA CO | 1983-11-18 | — | — | JP | disclosed |
| EP-0090340-A1 | Process for preparation of optically active 4-(2-Hydroxyethyl)-2-azetidinone | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-10-05 | — | — | EP | disclosed |