Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392318 | 0.93 | TSHR (0.59) | TSHRHTTLMNAKMT2APIK3CD | |
| SCHEMBL5158837 | 0.88 | TSHR (0.53) | TSHRHTTLMNAKMT2APIK3CD | |
| SCHEMBL948990 | 0.86 | TSHR (0.68) | TSHRHTTLMNAKMT2APIK3CD | |
| SCHEMBL9823072 | 0.83 | TSHR (0.44) | TSHRHTTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL948880 | 0.81 | TSHR (0.60) | TSHRHTTLMNAKMT2APIK3CD | |
| SCHEMBL596327 | 0.79 | TSHR (0.58) | TSHRHTTLMNAKMT2APIK3CD | |
| SCHEMBL11036951 | 0.79 | TSHR (0.58) | TSHRHTTLMNAKMT2APIK3CD | |
| SCHEMBL11259716 | 0.79 | TSHR (0.63) | TSHRHTTLMNAKMT2APIK3CD | |
| SCHEMBL9492570 | 0.78 | HTT (0.51) | TSHRHTTLMNAKMT2APIK3CD | |
| SCHEMBL10645521 | 0.77 | KMT2A (0.54) | TSHRHTTKMT2APIK3CDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |