Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823503 | 0.88 | IRAK4 (0.48) | TDP1TLR7ACHEIRAK4MAPT | |
| SCHEMBL9823137 | 0.87 | HTR2B (0.53) | TDP1TLR7IRAK4MAPTNPY1R | |
| SCHEMBL9823486 | 0.86 | HTR2B (0.52) | TDP1TLR7IRAK4MAPTNPY1R | |
| SCHEMBL9823568 | 0.85 | TDP1 (0.42) | TDP1TLR7ACHEIRAK4MAPT | |
| SCHEMBL9823416 | 0.85 | IRAK4 (0.51) | TDP1TLR7ACHEIRAK4CHEK1 | |
| SCHEMBL9823609 | 0.84 | IRAK4 (0.50) | TDP1TLR7ACHEIRAK4CHEK1 | |
| SCHEMBL9823630 | 0.84 | IRAK4 (0.50) | TDP1TLR7ACHEIRAK4CHEK1 | |
| SCHEMBL9823477 | 0.84 | TDP1 (0.64) | TDP1TLR7IRAK4MAPTNPY1R | |
| SCHEMBL9823191 | 0.84 | IRAK4 (0.42) | TDP1TLR7ACHEIRAK4MAPT | |
| Monoethanolamine SCHEMBL9823533 | 0.83 | HTR2B (0.49) | TDP1TLR7IRAK4MAPTNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262873-B1 | N-TETRAZOLYL THIAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4879295-A | ANTIALLERGENS | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0262873-A1 | N-tetrazolyl thiazolecarboxamide derivatives and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1988-04-06 | — | — | EP | disclosed |